Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223651 | 0.82 | CA12 (0.50) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL31043123 | 0.72 | — | — | |
| SCHEMBL1819400 | 0.72 | — | — | |
| SCHEMBL299004 | 0.72 | PARP1 (0.53) | CYP1A2 | |
| SCHEMBL30975576 | 0.72 | TDP2 (0.41) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL24855470 | 0.70 | TDP1 (0.39) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL299769 | 0.70 | TDP2 (0.52) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL2715285 | 0.69 | PARP1 (0.46) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL948923 | 0.68 | CA12 (0.63) | TDP2CES1KMT2AALDH1A1CA12 | |
| SCHEMBL30585092 | 0.68 | CA12 (0.63) | TDP2CES1KMT2AALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396936-B1 | Modulators of calcitonin and amylin receptor activity | KEMIA, INC. (US) | 2008-07-08 | — | — | US | disclosed |
| EP-0254052-A1 | 2-Mono and 2,3-bis (poly) chloromethyl) pyridines | THE DOW CHEMICAL COMPANY (US) | 1988-01-27 | — | — | EP | disclosed |
| US-4713460-A | 2,3-bis-(poly)(chloromethyl)pyridines | THE DOW CHEMICAL COMPANY (US) | 1987-12-15 | — | — | US | disclosed |