Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.86 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.86 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.66 |
| ▸ | DRD1 | P21728 | 2/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | DRD3 | P35462 | 2/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.66 |
| ▸ | BCL2 | P10415 | 1/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norchlorcyclizine SCHEMBL588655 | 1.00 | CYP2D6 (0.86) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| Norchlorcyclizine SCHEMBL6556514 | 1.00 | CYP2D6 (0.86) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| Norchlorcyclizine SCHEMBL4649874 | 0.98 | CYP2D6 (0.83) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| Norchlorcyclizine SCHEMBL588155 | 0.98 | CYP2D6 (0.83) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| Norchlorcyclizine SCHEMBL7139140 | 0.97 | CYP2D6 (0.81) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| SCHEMBL5363117 | 0.94 | CYP2D6 (0.76) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| SCHEMBL1137956 | 0.93 | CYP2D6 (1.00) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| Norchlorcyclizine SCHEMBL7989702 | 0.92 | CYP2D6 (0.73) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| Norchlorcyclizine SCHEMBL7993069 | 0.91 | CYP2D6 (0.71) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| Norchlorcyclizine SCHEMBL2426579 | 0.90 | CYP2D6 (0.69) | CYP2D6CYP19A1MEN1KMT2AOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120064494-A | Method for detecting p-chlorobenzhydryl piperazine in levocetirizine hydrochloride particles | 康芝药业股份有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-116203156-B | Detection method of cetirizine oral liquid preparation related impurities | 北京柏雅联合药物研究所有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-117209453-A | Preparation and application of levocetirizine hydrochloride intermediate | 迪嘉药业集团股份有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-116813490-A | Synthesis method of visible light driven unnatural amino acid and derivative thereof | 常州大学 | 2023-09-29 | — | — | CN | claimed |
| CN-114436765-B | Benzyl deuterated alpha, alpha-dideuterobenzyl iodide, dideuterobenzylamine and dideuterol drug molecules and synthesis method thereof | 中南大学 | 2023-03-31 | — | — | CN | claimed |
| CN-115417824-A | High-purity preparation method of rosuvastatin intermediate | 安徽美诺华药物化学有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-110726788-B | Method for separating and measuring levocetirizine hydrochloride and related substances thereof by high performance liquid chromatography | 湖南九典制药股份有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-114436765-A | Benzyl deuterated alpha, alpha-dideuterobenzyl iodide, dideuterobenzylamine and dideuterol drug molecules and synthesis method thereof | 中南大学 | 2022-05-06 | — | — | CN | claimed |
| CN-114163401-A | Preparation method and application of N-benzenesulfonyl formamidine compound | 商丘师范学院 | 2022-03-11 | — | — | CN | claimed |
| CN-113848271-A | Method for detecting related substances in levocetirizine hydrochloride oral solution | 浙江核力欣健药业有限公司 | 2021-12-28 | — | — | CN | claimed |
| EP-0617028-B1 | Enantiomers of 1-[(4-chlorophenyl)phenylmethyl]-4-[(4-methylphenyl)sulfonyl] piperazine | UCB SA (BE) | 2000-06-14 | — | — | EP | claimed |
| EP-0955295-A1 | Therapeutically active levorotatory and dextrorotatory 1-((4-chlorophenyl)phenylmethyl) piperazines | UCB, S.A. (BE) | 1999-11-10 | — | — | EP | claimed |
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| EP-0801064-A1 | Process for the preparation of 2-(2-(4((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-acetic acid and their salts | U C B, S.A. (BE) | 1997-10-15 | — | — | EP | claimed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0617028-A1 | Enantiomers of 1-(4-chlorophenyl)phenylmethyl)-4-(4-methylphenyl)sulfonyl piperazine | U C B, S.A. (BE) | 1994-09-28 | — | — | EP | claimed |