Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669406 | 0.73 | KCNA3 (0.31) | KCNA3MAOA | |
| SCHEMBL4669404 | 0.73 | KCNA3 (0.31) | KCNA3MAOA | |
| SCHEMBL4802949 | 0.72 | MAPT (0.38) | ALDH1A1MAPK1SMN1; SMN2KCNA3POLB | |
| SCHEMBL6664766 | 0.70 | — | — | |
| SCHEMBL6664726 | 0.68 | — | — | |
| SCHEMBL15449703 | 0.66 | ABL1 (0.39) | ALDH1A1MAPK1SMN1; SMN2POLBTSHR | |
| SCHEMBL2088751 | 0.66 | AHR (0.50) | ALDH1A1MAPK1KCNA3MAOATSHR | |
| SCHEMBL1858070 | 0.66 | SMN1; SMN2 (0.37) | ALDH1A1MAPK1SMN1; SMN2POLBKDM4E | |
| SCHEMBL9650168 | 0.65 | NQO2 (0.39) | ALDH1A1MAPK1SMN1; SMN2POLBKDM4E | |
| SCHEMBL4574258 | 0.64 | MAPT (0.44) | ALDH1A1MAPK1SMN1; SMN2MAOATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1116795-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE PYRIDINEETHANOL DERIVATIVES | KANEKA CORP (JP) | 2008-03-12 | — | — | EP | disclosed |
| US-7329518-B2 | Enzyme for producing optically active pyridineethanol derivatives | KANEKA CORPORATION (JP) | 2008-02-12 | — | — | US | disclosed |
| US-20040043460-A1 | Process for producing optically active pyridineethanol derivatives | KANEKA CORPORATION (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-1116795-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE PYRIDINEETHANOL DERIVATIVES | KANEKA CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |