SCHEMBL4574258

SCHEMBL4574258

CC(=O)c1cc(Cl)cc(C(C)=O)n1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
KDM1A O60341 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 1/20 0.38
TPMT P51580 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MAPK1 P28482 1/20 0.37
ALDH1A1 P00352 2/20 0.37
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
KMT2A Q03164 2/20 0.36
MAOB P27338 2/20 0.36
MAOA P21397 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
HIF1A Q16665 1/20 0.36
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9772756 0.89 MAPT (0.41) MAPTKDM1ASMN1; SMN2LMNATPMT
SCHEMBL6550051 0.87 KMT2A (0.42) MAPTKDM1ASMN1; SMN2LMNAL3MBTL1
SCHEMBL9297992 0.86 NQO2 (0.43) MAPTSMN1; SMN2L3MBTL1MAPK1ALDH1A1
SCHEMBL17878822 0.85 MAPT (0.39) MAPTKDM1ASMN1; SMN2LMNATPMT
SCHEMBL31581465 0.82 CYP1A2 (0.44) MAPTSMN1; SMN2LMNAALDH1A1RAB9A
SCHEMBL23526135 0.80 MAPT (0.36) MAPTKDM1ASMN1; SMN2L3MBTL1MAPK1
SCHEMBL29945706 0.80 MAPT (0.36) MAPTKDM1ASMN1; SMN2L3MBTL1MAPK1
SCHEMBL18298077 0.79 SMN1; SMN2 (0.42) MAPTKDM1ASMN1; SMN2ALDH1A1KMT2A
SCHEMBL744473 0.77 ALOX15 (0.61) LMNATPMTALOX15TSHRHIF1A
SCHEMBL5370102 0.77 SMN1; SMN2 (0.46) SMN1; SMN2LMNATPMTALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109206550-B Hybrid supermolecule dynamic polymer 厦门天策材料科技有限公司 2022-09-09 CN disclosed
CN-109207110-B Hybrid cross-linked dynamic polymer 厦门天策材料科技有限公司 2022-08-12 CN disclosed
EP-2793311-B1 METAL COMPLEX DYE, PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, DYE SOLUTION, AND COMPOUND FUJIFILM CORP (JP) 2019-06-19 EP disclosed
CN-109207110-A A kind of hybrid cross-linked dynamic aggregation object 翁秋梅 2019-01-15 CN disclosed
US-9564274-B2 Metal complex dye, photoelectric conversion element, dye-sensitized solar cell, dye solution, and compound FUJIFILM CORPORATION (JP) 2017-02-07 US disclosed
US-9564274-B2 Metal complex dye, photoelectric conversion element, dye-sensitized solar cell, dye solution, and compound FUJIFILM CORPORATION (JP) 2017-02-07 US disclosed
EP-2793311-A1 METAL COMPLEX DYE, PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, DYE SOLUTION, AND COMPOUND Fujifilm Corporation (JP) 2014-10-22 EP disclosed
US-20140290746-A1 METAL COMPLEX DYE, PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, DYE SOLUTION, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-10-02 US disclosed
US-20140290746-A1 METAL COMPLEX DYE, PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, DYE SOLUTION, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-10-02 US disclosed
US-8273875-B2 High performance luminescent compounds UNIVERSITY OF NOTRE DAME DU LAC (US) 2012-09-25 US disclosed
US-20050054856-A1 Catalysts containing N-pyrrolyl substituted nitrogen donors EASTMAN CHEMICAL COMPANY (US) 2005-03-10 US disclosed
US-6825356-B2 REMAINING DONOR ATOMS OF THE LIGAND ARE SELECTED FROM THE GROUP CONSISTING OF C, N, P, AS, O, S, AND SE EASTMAN CHEMICAL COMPANY 2004-11-30 US disclosed
US-20030225228-A1 Catalysts containing N-pyrrolyl substituted nitrogen donors EASTMAN CHEMICAL COMPANY 2003-12-04 US disclosed
US-20030195110-A1 Catalysts containing N-pyrrolyl substituted nitrogen donors E. I. DU PONT DE NEMOURS AND COMPANY 2003-10-16 US disclosed
US-6559091-B1 Metal complex ligated by a monodentate, bidentate, tridentate, or tetradentate ligand, wherein at least one of the donor atoms of the ligand is a nitrogen atom substituted by a 1-pyrrolyl or substituted 1- pyrrolyl group EASTMAN CHEMICAL COMPANY 2003-05-06 US disclosed
US-6545108-B1 Ti, Zr, Hf, Cr, Mo, W, V, Nb, or Ta complex of a monodentate dianionic ligand in which a nitrogen atom is substituted by a 1-pyrrolyl and the remaining donor atoms are N, P, As, O, S, or Se EASTMAN CHEMICAL COMPANY 2003-04-08 US disclosed
EP-1278784-A2 CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS EASTMAN CHEMICAL COMPANY (US) 2003-01-29 EP disclosed
EP-1192189-A2 CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS EASTMAN CHEMICAL COMPANY (US) 2002-04-03 EP disclosed
WO-2001083571-A2 CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS EASTMAN CHEMICAL COMPANY (US) 2001-11-08 WO disclosed
WO-2000050470-A2 CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS EASTMAN CHEMICAL COMPANY (US) 2000-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050054856-A1 Catalysts containing N-pyrrolyl substituted nitrogen donors NCL, NSFL1C, NCLN MAPT 1555/4885KDM1A 4771/4885SMN1; SMN2 2811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.