SCHEMBL4671087

SCHEMBL4671087

CCOC(=O)CC(C[N+](=O)[O-])C1(NC(=O)OC(C)(C)C)CCC1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.35
UGT2B7 P16662 2/20 0.31
CTSL P07711 1/20 0.31
CTSK P43235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9146864 0.95 CYP1A2 (0.36) CYP1A2CYP2C9CYP2C19HTTCTSL
SCHEMBL31149007 0.88 CYP1A2 (0.34) CYP1A2CYP2C9CYP2C19HTT
SCHEMBL4674223 0.80 UGT2B7 (0.40) CYP1A2CYP2C9CYP2C19HTTUGT2B7
SCHEMBL5234945 0.78 KLK7 (0.42) CTSL
SCHEMBL27555888 0.72
SCHEMBL19200954 0.71 CYP1A2 (0.43) CYP1A2CYP2C9CYP2C19HTTCTSL
SCHEMBL4675664 0.69 ITGB3 (0.34) CTSLCTSK
SCHEMBL7501049 0.68 CYP1A2 (0.41) CYP1A2CYP2C9CYP2C19HTTCTSK
SCHEMBL4675685 0.68 CYP1A2 (0.39) CYP1A2CYP2C9CYP2C19HTTCTSL
SCHEMBL30562226 0.67 CYP1A2 (0.39) CYP1A2CYP2C9CYP2C19HTTCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304329-B1 Pyridonecarboxylic acid derivatives and their use as antibacterial agents DAIICHI SANKYO CO LTD (JP) 2008-10-15 EP disclosed
EP-1304329-A2 Pyridonecarboxylic acid derivatives and their use as antibacterial agents DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-04-23 EP disclosed
US-5849757-A Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1998-12-15 US disclosed
EP-0807630-A1 HETEROCYCLIC COMPOUNDS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1997-11-19 EP disclosed