Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673240 | 0.83 | NPSR1 (0.42) | SMN1; SMN2NPSR1KDM4EHKDC1ALDH1A1 | |
| SCHEMBL4673235 | 0.83 | NPSR1 (0.42) | SMN1; SMN2NPSR1KDM4EHKDC1ALDH1A1 | |
| SCHEMBL4673246 | 0.83 | NPSR1 (0.42) | SMN1; SMN2NPSR1KDM4EHKDC1ALDH1A1 | |
| SCHEMBL4673211 | 0.81 | KDM4E (0.41) | SMN1; SMN2KDM4EHKDC1ALDH1A1MAPT | |
| SCHEMBL4674838 | 0.81 | KDM4E (0.41) | SMN1; SMN2KDM4EHKDC1ALDH1A1MAPT | |
| SCHEMBL4671613 | 0.80 | NPSR1 (0.41) | SMN1; SMN2NPSR1KDM4EHKDC1ALDH1A1 | |
| SCHEMBL6721749 | 0.80 | NPSR1 (0.41) | SMN1; SMN2NPSR1KDM4EHKDC1ALDH1A1 | |
| SCHEMBL15841495 | 0.74 | SMN1; SMN2 (0.77) | SMN1; SMN2ALDH1A1MAPTKMT2AHSD11B1 | |
| SCHEMBL9370383 | 0.74 | SMN1; SMN2 (0.77) | SMN1; SMN2ALDH1A1MAPTKMT2AHSD11B1 | |
| SCHEMBL9370376 | 0.74 | SMN1; SMN2 (0.77) | SMN1; SMN2ALDH1A1MAPTKMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375495-B1 | METHOD FOR PRODUCING A 2-AZETIDINONE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2008-09-03 | — | — | EP | disclosed |
| US-7126003-B2 | Method for producing 2-azetidinone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-10-24 | — | — | US | disclosed |
| US-20040072309-A1 | Method for producing 2-azetidinone derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1375495-A1 | METHOD FOR PRODUCING 2-AZETIDINONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072309-A1 | Method for producing 2-azetidinone derivative | CYP51A1, AZI2, POR | SMN1; SMN2 3693/4885NPSR1 4397/4885KDM4E 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.