Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673235 | 1.00 | NPSR1 (0.42) | NPSR1ALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL4673240 | 1.00 | NPSR1 (0.42) | NPSR1ALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL4168318 | 0.84 | SMN1; SMN2 (0.43) | NPSR1ALDH1A1TSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL4168315 | 0.84 | SMN1; SMN2 (0.43) | NPSR1ALDH1A1TSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL4168324 | 0.84 | SMN1; SMN2 (0.43) | NPSR1ALDH1A1TSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL4671101 | 0.83 | SMN1; SMN2 (0.57) | NPSR1ALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL4675295 | 0.82 | KDM4E (0.36) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL4675287 | 0.82 | KDM4E (0.36) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL4671531 | 0.82 | KDM4E (0.36) | ALDH1A1TSHRMEN1KMT2AKDM4E | |
| SCHEMBL4172914 | 0.82 | MEN1 (0.53) | NPSR1ALDH1A1MAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375495-B1 | METHOD FOR PRODUCING A 2-AZETIDINONE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2008-09-03 | — | — | EP | disclosed |
| US-7126003-B2 | Method for producing 2-azetidinone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-10-24 | — | — | US | disclosed |
| US-20040072309-A1 | Method for producing 2-azetidinone derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1375495-A1 | METHOD FOR PRODUCING 2-AZETIDINONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072309-A1 | Method for producing 2-azetidinone derivative | CYP51A1, AZI2, POR | NPSR1 4397/4885ALDH1A1 142/4885MAPT 4703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.