Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749798 | 0.87 | MEN1 (0.45) | SMN1; SMN2NPC1RAB9ACYP2C19RORC | |
| SCHEMBL2670272 | 0.87 | MEN1 (0.45) | SMN1; SMN2NPC1RAB9ACYP2C19RORC | |
| SCHEMBL4671023 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9ACYP2C19RORC | |
| SCHEMBL2670402 | 0.86 | RORC (0.42) | SMN1; SMN2NPC1RAB9ACYP2C19RORC | |
| SCHEMBL2670187 | 0.86 | RORC (0.42) | SMN1; SMN2NPC1RAB9ACYP2C19RORC | |
| SCHEMBL4671822 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9ACYP2C19RORC | |
| SCHEMBL2670295 | 0.82 | RORC (0.43) | SMN1; SMN2NPC1RAB9ACYP2C19RORC | |
| SCHEMBL2670258 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ACYP2C19RORC | |
| SCHEMBL2670255 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ACYP2C19RORC | |
| SCHEMBL14405539 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ACYP2C19RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304329-B1 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI SANKYO CO LTD (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5849757-A | Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |