Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 12/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669886 | 0.90 | MTNR1B (0.47) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL4669923 | 0.89 | SLC2A1 (0.46) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL4671352 | 0.89 | SLC2A1 (0.48) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL4671517 | 0.86 | SLC2A1 (0.44) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL4669677 | 0.86 | SLC2A1 (0.46) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL11929563 | 0.82 | SLC2A1 (0.47) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL4672221 | 0.82 | MC4R (0.51) | SLC2A1 | |
| SCHEMBL4671328 | 0.82 | SLC2A1 (0.43) | MTNR1AMTNR1BSLC2A1TSHRL3MBTL1 | |
| SCHEMBL14046526 | 0.81 | MTNR1B (0.41) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL11929578 | 0.79 | SLC2A1 (0.48) | SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1974729-A1 | Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists | Santhera Pharmaceuticals (Schweiz) AG (CH) | 2008-10-01 | — | — | EP | disclosed |