Glycerin

Glycerin

SCHEMBL4671978

O=C(O)O.OCC(O)CO.OCC(O)CO

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.69
ALDH1A1 P00352 1/20 0.69
OR51E2 Q9H255 1/20 0.50
SLC22A6 Q4U2R8 1/20 0.44
THRB P10828 1/20 0.44
PDE4A P27815 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
GABRR1 P24046 2/20 0.36
USP2 O75604 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 1/20 0.35
AKR1B1 P15121 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL30929982 1.00 LMNA (0.69) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL44491 1.00 LMNA (0.69) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL7030045 1.00 LMNA (0.69) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL28563108 1.00 LMNA (0.69) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL27943965 0.96 LMNA (0.64) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL29173218 0.96 LMNA (0.64) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL29173219 0.96 LMNA (0.64) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL28321773 0.96 LMNA (0.64) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL2231094 0.93 LMNA (0.60) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL8033638 0.93 LMNA (0.60) LMNAALDH1A1OR51E2SLC22A6THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677501-A Separation method of glycerol-glycerol carbonate mixed solution 河南大学 2023-02-03 CN claimed
CN-207250518-U Geiger mode avalanche photodiodes array, opto-electronic device and detecting system 意法半导体股份有限公司 2018-04-17 CN claimed
CN-107665886-A For detecting the geiger mode avalanche photodiodes array of infrared radiation 意法半导体股份有限公司 2018-02-06 CN claimed
US-20040110659-A1 Alkyl and/or alkenyl glycerol carbamates COGNIS DEUTSCHLAND GMBH & CO. KG (DE) 2004-06-10 US claimed
CN-116438120-A Aromatic diol compound, diepoxide compound, polymer prepared from such compound, and process for producing the same SWIMC有限公司 2023-07-14 CN disclosed
CN-115677501-A Separation method of glycerol-glycerol carbonate mixed solution 河南大学 2023-02-03 CN disclosed
CN-115677501-A Separation method of glycerol-glycerol carbonate mixed solution 河南大学 2023-02-03 CN disclosed
CN-115677501-A Separation method of glycerol-glycerol carbonate mixed solution 河南大学 2023-02-03 CN disclosed
CN-111704709-B Low-modulus solvent-free polyurethane resin for synthetic leather and preparation method thereof 上海华峰新材料研发科技有限公司 2022-01-28 CN disclosed
CN-111704709-A Low-modulus solvent-free polyurethane resin for synthetic leather and preparation method thereof 上海华峰新材料研发科技有限公司 2020-09-25 CN disclosed
EP-2998334-B1 CURABLE RESIN WITH SIGNIFICANT LEVELS OF CYCLIC CARBONATE GROUPS, AND CYCLOCARBONATE RESIN BASED FIXING SYSTEMS, THEIR PREPARATION AND USE FISCHERWERKE GMBH & CO KG (DE) 2020-03-25 EP disclosed
CN-109438244-A A method of glycerol carbonate is manufactured from glycerine and carbon dioxide 清华大学 2019-03-08 CN disclosed
WO-2012171659-A1 CARBONATE GROUP COMPRISING TERPENE-DERIVED MONOMERS AND ISOCYANATE-FREE POLYURETHANES ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2012-12-20 WO disclosed
EP-1981598-A2 PLASTICIZER OF NATURAL ORIGIN FOR NAIL POLISH Durlin France (FR) 2008-10-22 EP disclosed
WO-2007080172-A2 PLASTICIZER OF NATURAL ORIGIN FOR NAIL POLISH DURLIN FRANCE (FR) 2007-07-19 WO disclosed
US-20050038266-A1 Method for producing glycerol carbonate COGNIS DEUTSCHLAND GMBH & CO. KG (DE) 2005-02-17 US disclosed
US-20040110659-A1 Alkyl and/or alkenyl glycerol carbamates COGNIS DEUTSCHLAND GMBH & CO. KG (DE) 2004-06-10 US disclosed
US-20040110659-A1 Alkyl and/or alkenyl glycerol carbamates COGNIS DEUTSCHLAND GMBH & CO. KG (DE) 2004-06-10 US disclosed
US-3987004-A CYCLIC CARBONATE, AMINE ANTIOXIDANT NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1976-10-19 US disclosed
US-3985705-A AGAINST THERMAL DEGRADATION NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1976-10-12 US disclosed