Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608868 | 0.82 | EGFR (0.30) | — | |
| SCHEMBL14860415 | 0.82 | — | — | |
| SCHEMBL969567 | 0.81 | — | — | |
| SCHEMBL4431608 | 0.81 | — | — | |
| SCHEMBL28358269 | 0.79 | HDAC4 (0.34) | NPC1RAB9AHDAC8SMN1; SMN2 | |
| SCHEMBL10916917 | 0.78 | NPC1 (0.33) | NPC1RAB9A | |
| SCHEMBL1853429 | 0.78 | CYP1A2 (0.34) | KDM4ELMNACCR1CCR5CYP1A2 | |
| SCHEMBL16196932 | 0.78 | KDM4E (0.34) | KDM4EPOLBNOS3NOS1NOS2 | |
| SCHEMBL37815 | 0.77 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL115447 | 0.76 | CYP3A4 (0.33) | ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 522 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263912-A | Azanaphthyl substituted electricity-absorbing fragment compound and application thereof | 烟台显华科技集团股份有限公司 | 2023-12-22 | — | — | CN | claimed |
| US-20230374014-A1 | CGAS INHIBITING TRIAZOLOPYRIMIDONE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-11-23 | — | — | US | claimed |
| WO-2023055427-A1 | SMALL MOLECULE ANTAGONISTS OF PF4 | NEW YORK BLOOD CENTER, INC. (US) | 2023-04-06 | — | — | WO | claimed |
| EP-4153593-A1 | CGAS INHIBITING TRIAZOLOPYRIMIDONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-03-29 | — | — | EP | claimed |
| CN-115667265-A | CGAS-inhibiting triazolopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | claimed |
| US-11322695-B2 | Ink composition for organic light-emitting device, organic light-emitting device including film formed by using the ink composition, and method of manufacturing the organic light-emitting device | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2022-05-03 | — | — | US | claimed |
| WO-2021233852-A1 | CGAS INHIBITING TRIAZOLOPYRIMIDONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-11-25 | — | — | WO | claimed |
| CN-109311844-B | Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component | 东曹株式会社 | 2021-07-20 | — | — | CN | claimed |
| EP-3107898-B1 | 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-01-06 | — | — | EP | claimed |
| US-20200295273-A1 | INK COMPOSITION FOR ORGANIC LIGHT-EMITTING DEVICE, ORGANIC LIGHT-EMITTING DEVICE INCLUDING FILM FORMED BY USING THE INK COMPOSITION, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2020-09-17 | — | — | US | claimed |
| US-6153560-A | INSECTICIDE, FUNGICIDE, MITICIDE, NEMATOCIDE | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-28 | — | — | US | claimed |
| EP-0888311-A1 | PYRIMIDYL PHENYL AND BENZYL ETHERS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDE | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-07 | — | — | EP | claimed |
| WO-1997033874-A1 | PYRIMIDYL PHENYL AND BENZYL ETHERS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDE | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-18 | — | — | WO | claimed |
| EP-0262809-B1 | Pyrimidinylphenyl ester compound | TEIKOKU CHEM IND CO LTD (JP) | 1994-05-11 | — | — | EP | claimed |
| CN-1059521-A | The method and the intermediate that prepare 2-hydroxyl-3-thioether-3 phenylpropionic acid | SMITHKLINE BEECHAM CO (US) | 1992-03-18 | — | — | CN | claimed |
| EP-0321504-B1 | CHIRAL ARYLOXY PROPIONIC ACID ESTERS AND THEIR USE AS DOPING AGENT IN LIQUID CRYSTAL PHASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | claimed |
| US-5043094-A | Optically active bisaryl compound | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | claimed |
| US-4985172-A | CONVERT SMECTIIC INTO FERROELECTRIC LIQUID CRYSTALS | HOECHST AG (DE) | 1991-01-15 | — | — | US | claimed |
| EP-0321504-A1 | CHIRAL ARYLOXY PROPIONIC ACID ESTERS AND THEIR USE AS DOPING AGENT IN LIQUID CRYSTAL PHASES. | HOECHST AG (DE) | 1989-06-28 | — | — | EP | claimed |
| WO-1988003525-A1 | CHIRAL ARYLOXY PROPIONIC ACID ESTERS AND THEIR USE AS DOPING AGENT IN LIQUID CRYSTAL PHASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11322695-B2 | Ink composition for organic light-emitting device, organic light-emitting device including film formed by using the ink composition, and method of manufacturing the organic light-emitting device | TYR, IK, TH | KDM4E 137/4885LMNA 1894/4885CCR1 1320/4885 |
| US-20230374014-A1 | CGAS INHIBITING TRIAZOLOPYRIMIDONE DERIVATIVES | CGAS, GLS2, GBA3 | KDM4E 4276/4885LMNA 1616/4885CCR1 4098/4885 |
| US-20200295273-A1 | INK COMPOSITION FOR ORGANIC LIGHT-EMITTING DEVICE, ORGANIC LIGHT-EMITTING DEVICE INCLUDING FILM FORMED BY USING THE INK COMPOSITION, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT-EMITTING DEVICE | TYR, IK, TH | KDM4E 137/4885LMNA 1894/4885CCR1 1320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.