Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CCR1 | P32246 | 3/20 | 0.54 |
| ▸ | CCR5 | P51681 | 3/20 | 0.54 |
| ▸ | CCR8 | P51685 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9957877 | 0.84 | KDM4E (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL9957609 | 0.84 | KDM4E (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL712880 | 0.81 | CCR1 (0.53) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL9958223 | 0.80 | CYP2A6 (0.43) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL6349778 | 0.78 | CYP2A6 (0.48) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL583848 | 0.78 | METAP2 (0.40) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL712064 | 0.78 | MAPK14 (0.37) | HSP90AA1 | |
| SCHEMBL10812982 | 0.78 | KDM4E (0.48) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL467198 | 0.77 | KDM4E (0.35) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL16026579 | 0.77 | KDM4E (0.59) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2691 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307410-A | Preparation method of chiral secondary alcohol compound | 武汉大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118291125-A | Organic material composition and application thereof | 宁波卢米蓝新材料有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290414-A | Benzoxazole organic compound containing benzonaphthofuran and application thereof | 宁波卢米蓝新材料有限公司 | 2024-07-05 | — | — | CN | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| CN-117946149-A | Beta-alkyl substituted silane compound, preparation method and application thereof | 武汉大学 | 2024-04-30 | — | — | CN | claimed |
| CN-114456134-B | Alpha-fluoroalkyl substituted cyclopropyl alcohol compound, and preparation method and application thereof | 武汉大学 | 2024-04-26 | — | — | CN | claimed |
| CN-110431215-B | Organic electroluminescent compound and organic electroluminescent device comprising the same | 罗门哈斯电子材料韩国有限公司 | 2024-04-26 | — | — | CN | claimed |
| EP-3778576-B1 | 2-CYANOPYRIMIDIN-4-YL CARBAMATE OR UREA DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | HANLIM PHARMACEUTICAL CO LTD (KR) | 2024-04-17 | — | — | EP | claimed |
| CN-117820246-A | Cyclohexyl fluorene compound and application thereof | 上海飞凯材料科技股份有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117736183-A | Organic compound, preparation method thereof, organic electroluminescent device and display device | 上海飞凯材料科技股份有限公司 | 2024-03-22 | — | — | CN | claimed |
| EP-0664803-A1 | N-ARYLHETEROARYLALKYL 1-CYCLOALKYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1995-08-02 | — | — | EP | claimed |
| WO-1995012611-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | JAPAT LTD. (CH) | 1995-05-11 | — | — | WO | claimed |
| WO-1995006034-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1995-03-02 | — | — | WO | claimed |
| WO-1994008989-A1 | N-ARYLHETEROARYLALKYL 1-CYCLOALKYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1994-04-28 | — | — | WO | claimed |
| CN-1057257-A | The new intermediate of new imdazole derivatives and method for making thereof, gained, as the application of medicine with contain their pharmaceutical composition | ROUSSEL UCLAF (FR) | 1991-12-25 | — | — | CN | claimed |
| EP-0354553-A2 | Aryl cyanoguanidines: potassium channel activators and method of making same | E.R. SQUIBB & SONS, INC. (US) | 1990-02-14 | — | — | EP | claimed |
| US-4885294-A | AGRICULTURE, HUMANS | PFIZER INC. (US) | 1989-12-05 | — | — | US | claimed |
| WO-1989011283-A1 | ALDOPHOSPHAMIDE DERIVATIVES USEFUL AS ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1989-11-30 | — | — | WO | claimed |
| EP-0133109-A1 | Process for the N doping of polymers | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1985-02-13 | — | — | EP | claimed |
| EP-0034249-B1 | NEW NAPHTHIMIDAZOLE AND NAPHTHOXAZOLE DERIVATIVES, THEIR PREPARATION, AND THEIR USE IN PHARMACEUTICALS | GRUPPO LEPETIT S.P.A. (IT) | 1984-10-24 | — | — | EP | claimed |