Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 5/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 5/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 5/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.33 |
| ▸ | CDK9 | P50750 | 4/20 | 0.33 |
| ▸ | CDK1 | P06493 | 3/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.32 |
| ▸ | GSK3A | P49840 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | CDK7 | P50613 | 2/20 | 0.32 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5394721 | 0.99 | NPY5R (0.41) | NPY5RMAP4K1CCNKCDK12CUL4A | |
| SCHEMBL4679581 | 0.89 | CUL4A (0.44) | CUL4ACDK2CDK1CCNE1CCNE2 | |
| SCHEMBL4675962 | 0.85 | CHUK (0.42) | CUL4ACDK2CDK1CCNE1CCNE2 | |
| SCHEMBL4674125 | 0.76 | HTT (0.47) | OPRK1 | |
| Hydrochloric Acid SCHEMBL5387380 | 0.75 | HTT (0.46) | OPRK1 | |
| SCHEMBL4676435 | 0.75 | SMN1; SMN2 (0.43) | OPRK1 | |
| SCHEMBL4677592 | 0.74 | SMN1; SMN2 (0.45) | OPRK1 | |
| SCHEMBL4676746 | 0.73 | OPRK1 (0.40) | OPRK1 | |
| SCHEMBL13724515 | 0.72 | MAP4K1 (0.39) | NPY5RMAP4K1CCNKCDK12CUL4A | |
| SCHEMBL4674143 | 0.72 | JAK3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457199-B1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | OREAL (FR) | 2008-05-14 | — | — | EP | disclosed |
| US-7175670-B2 | Couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-02-13 | — | — | US | disclosed |
| US-7175670-B2 | Couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-02-13 | — | — | US | disclosed |
| EP-1457199-A1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | L'OREAL (FR) | 2004-09-15 | — | — | EP | disclosed |