Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29426998 | 1.00 | — | — | |
| SCHEMBL29502455 | 0.97 | — | — | |
| SCHEMBL300758 | 0.97 | — | — | |
| Methane SCHEMBL15323400 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL7950735 | 0.95 | — | — | |
| SCHEMBL31292048 | 0.95 | — | — | |
| Iodide SCHEMBL123176 | 0.95 | — | — | |
| Iodide SCHEMBL460164 | 0.95 | — | — | |
| Iodide SCHEMBL21810784 | 0.95 | — | — | |
| Bromide SCHEMBL379980 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097385-A1 | 2-[1-PHENYL-5-HYDROXY OR METHOXY-4ALPHA-METHYL-HEXAHYDROCLOPENTA[F]INDAZOL-5-YL]ETHYL PHENYL DERIVATIVES AS GLUCOCORTICOID RECEPTOR LIGANDS | Merck & Co., Inc. (US) | 2009-09-09 | — | — | EP | claimed |
| WO-2008051532-A1 | 2-[1-PHENYL-5-HYDROXY OR METHOXY-4ALPHA-METHYL-HEXAHYDROCLOPENTA[F]INDAZOL-5-YL]ETHYL PHENYL DERIVATIVES AS GLUCOCORTICOID RECEPTOR LIGANDS | MERCK & CO., INC. (US) | 2008-05-02 | — | — | WO | claimed |
| EP-0353640-B2 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE GMBH (DE) | 2003-10-15 | — | — | EP | claimed |
| EP-0353640-B1 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1995-04-12 | — | — | EP | claimed |
| EP-0353640-A2 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | Hoechst Schering AgrEvo GmbH (DE) | 1990-02-07 | — | — | EP | claimed |
| EP-3856179-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-05-13 | — | — | EP | disclosed |
| EP-4143193-B1 | IMIDAZOPYRIMIDINES AS MODULATORS OF IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2026-04-22 | — | — | EP | disclosed |
| US-12577243-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-17 | — | — | US | disclosed |
| EP-3856178-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-11 | — | — | EP | disclosed |
| US-12559496-B2 | Imidazopyrimidines as modulators of IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2026-02-24 | — | — | US | disclosed |
| EP-4103557-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-02-18 | — | — | EP | disclosed |
| US-12502378-B2 | Monoacylglycerol lipase modulators for use in autism spectrum disorders | JANSSEN PHARMACEUTICA NV (BE) | 2025-12-23 | — | — | US | disclosed |
| US-4939258-A | Cycloalkanol esters of dihydrolysergic acid | ELI LILLY AND COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0358432-A2 | 1,4-dihydropyridine derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-03-14 | — | — | EP | disclosed |
| US-4906639-A | Cycloalkanol esters of dihydrolysergic acid | ELI LILLY AND COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| WO-1989010941-A1 | CROSS-LINKED CARBOXY POLYSACCHARIDES | FIDIA S.P.A. (IT) | 1989-11-16 | — | — | WO | disclosed |
| EP-0341745-A1 | Crosslinked carboxy polysaccharides | FIDIA S.p.A. (IT) | 1989-11-15 | — | — | EP | disclosed |
| US-4845224-A | Cycloalkanol esters of dihydrolysergic acid having peripheral serotonin antagonist properties | ELI LILLY AND COMPANY (US) | 1989-07-04 | — | — | US | disclosed |
| US-4683236-A | ANTISEROTONIN AGENTS | ELI LILLY AND COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| EP-0219257-A2 | Esters of dihydrolysergic acid | ELI LILLY AND COMPANY (US) | 1987-04-22 | — | — | EP | disclosed |