Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065952 | 0.90 | PTGDR2 (0.55) | PTGDR2PTGDR | |
| SCHEMBL883837 | 0.89 | PTGDR2 (0.48) | PTGDR2PTGDR | |
| SCHEMBL885411 | 0.89 | PTGDR2 (0.48) | PTGDR2PTGDR | |
| SCHEMBL586145 | 0.88 | NR3C1 (0.48) | PTGDR2 | |
| SCHEMBL587091 | 0.88 | PTGDR2 (0.47) | PTGDR2THRATHRBPTGDR | |
| SCHEMBL586266 | 0.86 | PTGDR2 (0.46) | PTGDR2THRATHRB | |
| SCHEMBL883843 | 0.85 | PTGDR2 (0.56) | PTGDR2 | |
| SCHEMBL10121231 | 0.85 | PTGDR2 (0.45) | PTGDR2PTGDR | |
| SCHEMBL10144402 | 0.85 | PTGDR2 (0.45) | PTGDR2PTGDR | |
| SCHEMBL1651360 | 0.83 | EPAS1 (0.49) | PTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937632-A1 | NOVEL COMPOUNDS | Astra Zeneca AB (SE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007039736-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-04-12 | — | — | WO | disclosed |