Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.54 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4674578 | 1.00 | MEN1 (0.55) | MEN1KMT2APRMT5WDR77KCNH2 | |
| SCHEMBL1831673 | 0.88 | SMN1; SMN2 (0.47) | MEN1KMT2APRMT5WDR77L3MBTL1 | |
| SCHEMBL1831669 | 0.88 | SMN1; SMN2 (0.47) | MEN1KMT2APRMT5WDR77L3MBTL1 | |
| SCHEMBL3636867 | 0.84 | SMN1; SMN2 (0.43) | MEN1KMT2APRMT5WDR77L3MBTL1 | |
| SCHEMBL3636237 | 0.84 | RORC (0.49) | MEN1KMT2AL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL3636119 | 0.84 | SMN1; SMN2 (0.43) | MEN1KMT2APRMT5WDR77L3MBTL1 | |
| SCHEMBL3636241 | 0.84 | RORC (0.49) | MEN1KMT2AL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL1838495 | 0.82 | SMN1; SMN2 (0.43) | MEN1KMT2AKCNH2HRH3L3MBTL1 | |
| SCHEMBL1838492 | 0.82 | SMN1; SMN2 (0.43) | MEN1KMT2AKCNH2HRH3L3MBTL1 | |
| SCHEMBL3636445 | 0.81 | CHRM2 (0.46) | MEN1KMT2APRMT5WDR77ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |