Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 4/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673267 | 1.00 | HTT (0.35) | HTTSMN1; SMN2TERTCNR1HTR6 | |
| SCHEMBL4673163 | 1.00 | HTT (0.35) | HTTSMN1; SMN2TERTCNR1HTR6 | |
| SCHEMBL4671088 | 1.00 | HTT (0.35) | HTTSMN1; SMN2TERTCNR1HTR6 | |
| SCHEMBL6321380 | 1.00 | HTT (0.35) | HTTSMN1; SMN2TERTCNR1HTR6 | |
| SCHEMBL4673869 | 0.96 | PRKDC (0.39) | HTTSMN1; SMN2PRKDCDPP4 | |
| SCHEMBL4677173 | 0.96 | PRKDC (0.39) | HTTSMN1; SMN2PRKDCDPP4 | |
| SCHEMBL4676232 | 0.96 | PRKDC (0.39) | HTTSMN1; SMN2PRKDCDPP4 | |
| SCHEMBL4670960 | 0.96 | PRKDC (0.39) | HTTSMN1; SMN2PRKDCDPP4 | |
| SCHEMBL4670962 | 0.95 | PRKDC (0.39) | HTTSMN1; SMN2PRKDCDPP4 | |
| SCHEMBL4670953 | 0.94 | IDH1 (0.33) | HTTSMN1; SMN2TERTCNR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461330-B1 | 3H-NAPHTHO[2,1-b]-PYRANE DERIVATIVES AND THEIR USE | RODENSTOCK GMBH (DE) | 2008-03-12 | — | — | EP | claimed |
| EP-1461330-B1 | 3H-NAPHTHO[2,1-b]-PYRANE DERIVATIVES AND THEIR USE | RODENSTOCK GMBH (DE) | 2008-03-12 | — | — | EP | disclosed |