Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4678679 | 0.88 | PDE4B (0.61) | PDE4BADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL1652438 | 0.85 | PDE4B (0.54) | PDE4BACHEBACE1 | |
| SCHEMBL4708766 | 0.84 | PDE4B (0.70) | PDE4BADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL4678908 | 0.83 | PDE4B (0.67) | PDE4BSMN1; SMN2 | |
| SCHEMBL4705575 | 0.82 | PDE4B (0.70) | PDE4BADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL4708054 | 0.81 | PDE4B (0.69) | PDE4BADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL3039579 | 0.81 | PDE4B (0.67) | PDE4BSMN1; SMN2 | |
| SCHEMBL3028554 | 0.81 | PDE4B (0.61) | PDE4BSMN1; SMN2 | |
| SCHEMBL3028418 | 0.81 | PDE4B (0.56) | PDE4BACHEBACE1SMN1; SMN2 | |
| SCHEMBL4706461 | 0.81 | PDE4B (0.74) | PDE4BADRA1AADRA1BADRA1DHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575926-B1 | NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES | ALMIRALL LAB (ES) | 2008-03-05 | — | — | EP | claimed |