Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.67 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039579 | 0.93 | PDE4B (0.67) | PDE4BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4674784 | 0.92 | PDE4B (0.56) | PDE4BPABPC1NPC1MEN1POLB | |
| SCHEMBL4675165 | 0.90 | PDE4B (0.54) | PDE4BNPC1MEN1POLBKMT2A | |
| SCHEMBL4674749 | 0.89 | PDE4B (0.52) | PDE4BPABPC1ABCB1ABCC1ABCG2 | |
| SCHEMBL4706461 | 0.88 | PDE4B (0.74) | PDE4BSMN1; SMN2MAPT | |
| SCHEMBL4677346 | 0.87 | PDE4B (0.67) | PDE4BSMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL3032321 | 0.85 | PDE4B (0.64) | PDE4BSMN1; SMN2 | |
| SCHEMBL4678679 | 0.85 | PDE4B (0.61) | PDE4BSMN1; SMN2 | |
| SCHEMBL3039908 | 0.84 | PDE4B (0.66) | PDE4BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4675156 | 0.83 | PDE4B (0.59) | PDE4BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575926-B1 | NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES | ALMIRALL LAB (ES) | 2008-03-05 | — | — | EP | claimed |