Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.37 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671198 | 0.86 | CYP3A4 (0.46) | CYP3A4DPP4ALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL2082137 | 0.82 | STAT3 (0.41) | STAT3HTTCYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL2082138 | 0.82 | STAT3 (0.41) | STAT3HTTCYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL2078701 | 0.81 | STAT3 (0.43) | STAT3HTTCYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL2078703 | 0.81 | STAT3 (0.43) | STAT3HTTCYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL4675217 | 0.79 | STAT3 (0.40) | STAT3HTTDPP4GNRHRALDH1A1 | |
| SCHEMBL13483600 | 0.78 | STAT3 (0.52) | STAT3HTTALDH1A1TSHRKDM4E | |
| SCHEMBL9096244 | 0.78 | STAT3 (0.62) | STAT3HTTALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL8539874 | 0.78 | STAT3 (0.62) | STAT3HTTALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL4672032 | 0.78 | STAT3 (0.62) | STAT3HTTALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304329-B1 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI SANKYO CO LTD (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |