Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672032 | 1.00 | STAT3 (0.62) | STAT3HTTTSHRCASP1ADRB2 | |
| SCHEMBL9096244 | 1.00 | STAT3 (0.62) | STAT3HTTTSHRCASP1ADRB2 | |
| SCHEMBL7997863 | 0.93 | STAT3 (0.54) | STAT3HTTTSHRCASP1ADRB2 | |
| SCHEMBL8744098 | 0.93 | STAT3 (0.54) | STAT3HTTTSHRCASP1ADRB2 | |
| SCHEMBL13483600 | 0.91 | STAT3 (0.52) | STAT3HTTTSHRCASP1ADRB2 | |
| SCHEMBL13483601 | 0.88 | STAT3 (0.48) | STAT3HTTTSHRCASP1ADRB2 | |
| SCHEMBL1345146 | 0.86 | STAT3 (0.65) | STAT3HTTTSHRCASP1ADRB2 | |
| SCHEMBL10365215 | 0.84 | STAT3 (0.55) | STAT3HTTADRB2KDM4EALDH1A1 | |
| SCHEMBL4671582 | 0.84 | STAT3 (0.46) | STAT3HTTTSHRCASP1ADRB2 | |
| SCHEMBL8537622 | 0.84 | STAT3 (0.45) | STAT3HTTTSHRCASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545642-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | claimed |
| US-5849757-A | Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| US-5545642-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | disclosed |