Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.62 |
| ▸ | RAB9A | P51151 | 12/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.62 |
| ▸ | PKM | P14618 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.50 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15987471 | 0.79 | NPC1 (0.58) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30561047 | 0.78 | NPC1 (1.00) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30634854 | 0.78 | NPC1 (1.00) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL172216 | 0.78 | NPC1 (1.00) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| Water SCHEMBL9817804 | 0.76 | NPC1 (0.95) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL82498 | 0.76 | NPC1 (0.58) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15771070 | 0.75 | NPC1 (0.57) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8485230 | 0.75 | NPC1 (0.57) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15987644 | 0.75 | NPC1 (0.56) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3795975 | 0.73 | ALDH1A1 (0.59) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220161-A1 | POLYIMIDE PRECURSOR PREPARED BY USING POLYCYCLIC MONOMER INCLUDING TRIFLUOROMETHYL GROUP AND FLEXIBLE POLYIMIDE OBTAINED BY USING THE SAME | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2023-07-13 | — | — | US | claimed |
| CN-114361341-A | Laminated image pickup device and image pickup module | 索尼公司 | 2022-04-15 | — | — | CN | claimed |
| CN-107534050-B | Image sensor, laminated image pickup device, and image pickup module | 索尼公司 | 2021-12-14 | — | — | CN | claimed |
| CN-111316459-A | Photoelectric conversion element and imaging device | 索尼公司 | 2020-06-19 | — | — | CN | claimed |
| US-10566548-B2 | Image sensor, stacked imaging device and imaging module | SONY CORPORATION (JP) | 2020-02-18 | — | — | US | claimed |
| EP-3300114-B1 | IMAGING ELEMENT, MULTILAYER IMAGING ELEMENT AND IMAGING DEVICE | SONY CORP (JP) | 2020-01-08 | — | — | EP | claimed |
| US-20180114926-A1 | IMAGE SENSOR, STACKED IMAGING DEVICE AND IMAGING MODULE | SONY CORPORATION (JP) | 2018-04-26 | — | — | US | claimed |
| EP-3300114-A1 | IMAGING ELEMENT, MULTILAYER IMAGING ELEMENT AND IMAGING DEVICE | Sony Corporation (JP) | 2018-03-28 | — | — | EP | claimed |
| CN-107534050-A | image sensor, laminated image pickup device, and image pickup module | 索尼公司 | 2018-01-02 | — | — | CN | claimed |
| CN-105441067-B | Organic electroluminescent material as well as preparation method and application thereof | 中节能万润股份有限公司 | 2017-05-24 | — | — | CN | claimed |
| US-8501754-B2 | Quinazolinamide derivatives | MERCK PATENT GMBH (DE) | 2013-08-06 | — | — | US | claimed |
| WO-2012059442-A2 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2012-05-10 | — | — | WO | claimed |
| CN-101875637-A | Organic material and application thereof in organic electroluminescence devices | BEIJING VISIONOX TECHNOLOGY CO | 2010-11-03 | — | — | CN | claimed |
| US-20100234324-A1 | Quinazolinamide derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-09-16 | — | — | US | claimed |
| EP-2164833-A2 | QUINAZOLINAMIDE DERIVATIVES | Merck Patent GmbH (DE) | 2010-03-24 | — | — | EP | claimed |
| WO-2009010139-A2 | QUINAZOLINAMIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-01-22 | — | — | WO | claimed |
| US-5501850-A | COSMETICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-26 | — | — | US | claimed |
| EP-0581955-A1 | USE OF BENZIMIDAZOLE DERIVATIVES AS PROTECTIVE LIGHT FILTERS. | MERCK PATENT GMBH (DE) | 1994-02-09 | — | — | EP | claimed |
| WO-1993015712-A1 | USE OF BENZIMIDAZOLE DERIVATIVES AS PROTECTIVE LIGHT FILTERS | MERCK PATENT GMBH (DE) | 1993-08-19 | — | — | WO | claimed |
| EP-0163237-A2 | Di- and tri-peptidal renin inhibitors | MERCK & CO. INC. (US) | 1985-12-04 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234324-A1 | Quinazolinamide derivatives | HSP90AB1, HSP90AA1, HSP90AB2P | NPC1 1106/4885RAB9A 790/4885ALDH1A1 1776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.