Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672078 | 0.90 | PPARD (0.50) | NPC1MAPTRAB9AMCL1PPARD | |
| SCHEMBL4674023 | 0.88 | RAB9A (0.55) | NPC1MAPTRAB9APPARDPPARA | |
| SCHEMBL4675305 | 0.88 | MAPT (0.58) | NPC1MAPTRAB9APPARDPPARA | |
| SCHEMBL4671833 | 0.88 | BCHE (0.48) | NPC1MAPTRAB9APPARDPPARA | |
| SCHEMBL3560701 | 0.82 | MAPT (0.54) | NPC1MAPTRAB9AMCL1HSP90AA1 | |
| SCHEMBL4671246 | 0.79 | PPARD (0.47) | MAPTPPARDPPARARXRARXRB | |
| SCHEMBL4671589 | 0.77 | EIF4E (0.42) | NPC1RAB9AMAOB | |
| SCHEMBL4675225 | 0.73 | MAPT (0.45) | NPC1MAPTRAB9APPARDPPARA | |
| SCHEMBL3568125 | 0.71 | MAPT (0.56) | NPC1MAPTRAB9AMCL1PPARD | |
| SCHEMBL3556746 | 0.69 | MAPT (0.72) | NPC1MAPTRAB9APPARDHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663936-B1 | BIARYLOXYMETHYLARENE-CARBOXYLIC ACIDS | HOFFMANN LA ROCHE (CH) | 2008-01-09 | — | — | EP | claimed |