Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.58 |
| ▸ | MC3R | P41968 | 2/20 | 0.51 |
| ▸ | MC5R | P33032 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684524 | 0.93 | MC4R (0.57) | MC4RMC3RMC5R | |
| SCHEMBL4684497 | 0.91 | MC4R (0.55) | MC4RMC3RMC5R | |
| SCHEMBL4679990 | 0.90 | MC4R (0.54) | MC4RMC3RMC5R | |
| SCHEMBL4682221 | 0.87 | MC4R (0.58) | MC4RMC3RMC5R | |
| SCHEMBL4678973 | 0.86 | MC4R (0.55) | MC4RMC3RMC5R | |
| SCHEMBL4679458 | 0.84 | MC4R (0.81) | MC4RMC3RMC5R | |
| SCHEMBL4680937 | 0.83 | MC4R (0.58) | MC4RMC3RMC5R | |
| SCHEMBL5475017 | 0.83 | MC4R (0.70) | MC4RMC3RMC5R | |
| SCHEMBL4680491 | 0.81 | MC4R (0.55) | MC4RMC3RMC5R | |
| SCHEMBL5475821 | 0.81 | MC4R (0.67) | MC4RMC3RMC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417190-B1 | SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC (US) | 2008-10-22 | — | — | EP | claimed |