Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.70 |
| ▸ | MC5R | P33032 | 2/20 | 0.56 |
| ▸ | MC3R | P41968 | 2/20 | 0.56 |
| ▸ | MC1R | Q01726 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475821 | 0.92 | MC4R (0.67) | MC4RMC5RMC3R | |
| SCHEMBL4684524 | 0.90 | MC4R (0.57) | MC4RMC5RMC3RMC1R | |
| SCHEMBL4677014 | 0.83 | MC4R (0.58) | MC4RMC5RMC3R | |
| SCHEMBL4684497 | 0.82 | MC4R (0.55) | MC4RMC5RMC3R | |
| SCHEMBL4679990 | 0.79 | MC4R (0.54) | MC4RMC5RMC3R | |
| SCHEMBL4677487 | 0.79 | MC4R (0.55) | MC4R | |
| SCHEMBL4521394 | 0.78 | MC4R (0.72) | MC4RMC5RMC3RCCR1 | |
| SCHEMBL4682221 | 0.75 | MC4R (0.58) | MC4RMC5RMC3R | |
| SCHEMBL4678973 | 0.74 | MC4R (0.55) | MC4RMC5RMC3RMC1R | |
| SCHEMBL4680937 | 0.73 | MC4R (0.58) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265248-A1 | Substituted piperazines and methods of use | AMGEN INC. (US) | 2007-11-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265248-A1 | Substituted piperazines and methods of use | MC5R, MC4R, MC1R | MC4R 2/4885MC5R 1/4885MC3R 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.