Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.64 |
| ▸ | PRKCA | P17252 | 6/20 | 0.64 |
| ▸ | PRKCB | P05771 | 6/20 | 0.64 |
| ▸ | PRKCG | P05129 | 4/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.57 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.55 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069262 | 0.84 | GSK3B (0.71) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL4682932 | 0.81 | GSK3B (0.67) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL3774109 | 0.81 | GSK3B (0.66) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL4740834 | 0.80 | GSK3B (0.65) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL13670446 | 0.80 | GSK3B (0.65) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL6242476 | 0.79 | GSK3B (0.44) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL1127716 | 0.79 | GSK3B (0.64) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL3773898 | 0.78 | GSK3B (1.00) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL1127978 | 0.78 | GSK3B (0.63) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL8161694 | 0.77 | GSK3B (1.00) | GSK3BPRKCACAMK2DCDK2CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513520-B1 | SUBSTITUTED PYRROLINES AS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-09-24 | — | — | EP | disclosed |