Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 16/20 | 0.59 |
| ▸ | PRKCB | P05771 | 11/20 | 0.59 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.54 |
| ▸ | PRKCG | P05129 | 9/20 | 0.52 |
| ▸ | PRKCA | P17252 | 9/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | FLT3 | P36888 | 2/20 | 0.52 |
| ▸ | QPCT | Q16769 | 2/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954384 | 0.82 | GSK3B (0.56) | GSK3BPRKCBCAMK2DPRKCGPRKCA | |
| SCHEMBL3781580 | 0.77 | GSK3B (0.66) | GSK3BPRKCBPRKCGPRKCA | |
| SCHEMBL5757131 | 0.76 | GSK3B (0.65) | GSK3BPRKCBCAMK2DPRKCGPRKCA | |
| SCHEMBL3779590 | 0.75 | GSK3B (0.79) | GSK3BPRKCBCAMK2DPRKCGPRKCA | |
| SCHEMBL3784374 | 0.74 | PRKCA (0.76) | GSK3BPRKCBCAMK2DPRKCGPRKCA | |
| SCHEMBL3774788 | 0.74 | GSK3B (0.80) | GSK3BPRKCBCAMK2DPRKCGPRKCA | |
| SCHEMBL2982584 | 0.74 | GSK3B (1.00) | GSK3BPRKCBPRKCGPRKCAIDH1 | |
| SCHEMBL5756314 | 0.74 | PRKCA (0.73) | GSK3BPRKCBPRKCGPRKCAIDH1 | |
| SCHEMBL4339857 | 0.74 | GSK3B (0.55) | GSK3BPRKCBCAMK2DPRKCGPRKCA | |
| SCHEMBL5759900 | 0.74 | GSK3B (0.80) | GSK3BPRKCBCAMK2DPRKCGPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513520-B1 | SUBSTITUTED PYRROLINES AS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-09-24 | — | — | EP | disclosed |