Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NEK2 | P51955 | 3/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673141 | 0.81 | OPRK1 (0.37) | OPRK1 | |
| SCHEMBL4673286 | 0.80 | OPRK1 (0.35) | OPRK1 | |
| SCHEMBL4679153 | 0.79 | OPRK1 (0.38) | OPRK1KEAP1NFE2L2 | |
| SCHEMBL4679460 | 0.77 | OPRK1 (0.38) | OPRK1 | |
| SCHEMBL4676456 | 0.75 | SMN1; SMN2 (0.47) | OPRK1NEK2KEAP1NFE2L2 | |
| SCHEMBL4676449 | 0.75 | SMN1; SMN2 (0.47) | OPRK1NEK2KEAP1NFE2L2 | |
| SCHEMBL4676435 | 0.74 | SMN1; SMN2 (0.43) | OPRK1NEK2KEAP1NFE2L2 | |
| SCHEMBL4677592 | 0.73 | SMN1; SMN2 (0.45) | OPRK1NEK2KEAP1NFE2L2 | |
| SCHEMBL4676746 | 0.72 | OPRK1 (0.40) | OPRK1 | |
| SCHEMBL4679996 | 0.68 | OPRK1 (0.34) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457199-B1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | OREAL (FR) | 2008-05-14 | — | — | EP | disclosed |
| US-7175670-B2 | Couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-02-13 | — | — | US | disclosed |
| US-20050081313-A1 | Novel couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2005-04-21 | — | — | US | disclosed |
| EP-1459732-A1 | Dye composition comprising at least one heterocyclic oxidation base and at least one 2,3,5-triaminopyridine as coupler | L'OREAL (FR) | 2004-09-22 | — | — | EP | disclosed |
| EP-1457199-A1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | L'OREAL (FR) | 2004-09-15 | — | — | EP | disclosed |