Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 3/20 | 0.39 |
| ▸ | TOP2A | P11388 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948982 | 0.89 | KCNH2 (0.49) | KCNH2KDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL4677287 | 0.85 | KCNH2 (0.53) | KCNH2SCN5AKDM4EKMT2AALDH1A1 | |
| SCHEMBL15090830 | 0.84 | KCNH2 (0.50) | KCNH2SCN5AKDM4EKMT2AALDH1A1 | |
| SCHEMBL7511355 | 0.80 | KCNH2 (0.65) | KCNH2SCN5AKDM4EKMT2AALDH1A1 | |
| SCHEMBL8383857 | 0.80 | KCNH2 (0.57) | KCNH2KDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL6967038 | 0.80 | CACNA1F (0.48) | KCNH2KMT2APOLBTOP2A | |
| SCHEMBL15726080 | 0.78 | KCNH2 (0.51) | KCNH2SCN5AKDM4EKMT2AALDH1A1 | |
| SCHEMBL14343329 | 0.78 | KCNH2 (0.51) | KCNH2SCN5AKDM4EKMT2AALDH1A1 | |
| SCHEMBL6529669 | 0.77 | KCNH2 (0.67) | KCNH2SCN5AKDM4EKMT2AALDH1A1 | |
| SCHEMBL8940663 | 0.76 | KCNH2 (0.67) | KCNH2KDM4EKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807630-B1 | HETEROCYCLIC COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2003-05-07 | — | — | EP | claimed |
| EP-1304329-B1 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI SANKYO CO LTD (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-0807630-B1 | HETEROCYCLIC COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |