Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29213125 | 0.91 | KMT2A (0.49) | KMT2AESR1ESR2MEN1TSHR | |
| SCHEMBL27846661 | 0.86 | KMT2A (0.55) | KMT2AESR1ESR2MEN1TSHR | |
| SCHEMBL27640925 | 0.84 | ESR1 (0.68) | KMT2AESR1ESR2L3MBTL1PTGS1 | |
| SCHEMBL8550655 | 0.84 | SMN1; SMN2 (0.54) | KMT2AMEN1TSHRSMN1; SMN2MAPT | |
| SCHEMBL18381729 | 0.83 | KMT2A (0.60) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL174166 | 0.83 | KMT2A (0.60) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL30870371 | 0.83 | KMT2A (0.60) | KMT2AESR1ESR2MEN1TSHR | |
| SCHEMBL5812804 | 0.83 | KMT2A (0.60) | KMT2AESR1ESR2MEN1TSHR | |
| SCHEMBL18381730 | 0.83 | KMT2A (0.60) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL29425354 | 0.83 | KMT2A (0.60) | KMT2AMEN1L3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108276374-B | Flavonoid aromatase inhibitor and preparation method and application thereof | 天津科技大学 | 2020-01-31 | — | — | CN | disclosed |
| WO-2018048924-A1 | GEL NETWORK HAIR TREATMENT COMPOSITIONS WITH REDUCED ODOR | NOXELL CORPORATION (US) | 2018-03-15 | — | — | WO | disclosed |
| CN-100491323-C | Biaryloxymethylarenecarboxylic acids compound | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | CN | disclosed |
| EP-1663936-B1 | BIARYLOXYMETHYLARENE-CARBOXYLIC ACIDS | HOFFMANN LA ROCHE (CH) | 2008-01-09 | — | — | EP | disclosed |
| US-20060287527-A1 | Process for producing acrylic acid derivative | NIPPON SODA CO., LTD. (JP) | 2006-12-21 | — | — | US | disclosed |
| CN-1812956-A | Biaryloxymethylarenecarboxylic acids as glycogen synthase activator | HOFFMANN LA ROCHE (CH) | 2006-08-02 | — | — | CN | disclosed |
| CN-1205171-C | Process for producing 2-halomethylphenylacetic acid esters | SAGAMI CHEM RES (JP) | 2005-06-08 | — | — | CN | disclosed |
| CN-1186309-C | Process for producing 3-isochromanone | SAGAMI CHEM RES (JP) | 2005-01-26 | — | — | CN | disclosed |
| CN-1566072-A | Method for preparing 2-halomethyl phenylacetiate | SAGAMI CHEM RES (JP) | 2005-01-19 | — | — | CN | disclosed |
| CN-1168718-C | Process for preparation of 2-(6-substituted pyrid-2-yloxymethyl) phenylacetate | — | 2004-09-29 | — | — | CN | disclosed |
| US-20040152894-A1 | Process for producing acrylic acid derivative | NIPPON SODA CO. LTD (JP) | 2004-08-05 | — | — | US | disclosed |
| CN-1105105-C | Process for preparing 2- (pyridin-2-yloxymethyl) phenylacetates as intermediates in insecticides | ZENECA LTD (GB) | 2003-04-09 | — | — | CN | disclosed |
| CN-1328991-A | Process for producing 2-halomethylphenylacetic acid esters | SAGAMI CHEMICA RES CT (JP) | 2002-01-02 | — | — | CN | disclosed |
| EP-1142857-A1 | PROCESSES FOR PRODUCING ACRYLIC ACID DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| CN-1198740-A | Process for preparing 2- (pyridin-2-yloxymethyl) phenylacetates as intermediates in insecticides | ZENECA LTD (GB) | 1998-11-11 | — | — | CN | disclosed |
| CN-1193314-A | Process for producing 2-halomethylphenylacetic acid esters | SAGAMI CHEM RES (JP) | 1998-09-16 | — | — | CN | disclosed |
| CN-1189155-A | Process for preparation of 2-(6-substituted pyrid-2-yloxymethyl) phenylacetate | ZENECA LTD (GB) | 1998-07-29 | — | — | CN | disclosed |
| EP-0506794-A1 | NOVEL VITAMIN D ANALOGUES. | LEO PHARM PROD LTD (DK) | 1992-10-07 | — | — | EP | disclosed |
| WO-1991009841-A1 | NOVEL VITAMIN D ANALOGUES | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1991-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152894-A1 | Process for producing acrylic acid derivative | OXGR1, GART, HAO2 | KMT2A 938/4885ESR1 2243/4885ESR2 3302/4885 |
| US-20060287527-A1 | Process for producing acrylic acid derivative | APEH, HAAO, ASNS | KMT2A 696/4885ESR1 1321/4885ESR2 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.