Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11176235 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EL3MBTL1TDP1 | |
| SCHEMBL4677493 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EL3MBTL1TDP1 | |
| SCHEMBL22259113 | 0.86 | MAPT (0.59) | ALDH1A1HPGDKDM4EL3MBTL1MEN1 | |
| SCHEMBL2820796 | 0.83 | KDM4E (0.69) | ALDH1A1HPGDKDM4EL3MBTL1TDP1 | |
| SCHEMBL2820798 | 0.83 | KDM4E (0.69) | ALDH1A1HPGDKDM4EL3MBTL1TDP1 | |
| SCHEMBL28572859 | 0.82 | KDM4E (0.61) | ALDH1A1HPGDKDM4EL3MBTL1TDP1 | |
| SCHEMBL30395765 | 0.82 | KDM4E (0.61) | ALDH1A1HPGDKDM4EL3MBTL1TDP1 | |
| SCHEMBL28996362 | 0.82 | KDM4E (0.61) | ALDH1A1HPGDKDM4EL3MBTL1TDP1 | |
| SCHEMBL9764623 | 0.80 | ALDH1A1 (0.69) | ALDH1A1HPGDKDM4EL3MBTL1TDP1 | |
| SCHEMBL29637242 | 0.80 | ALDH1A1 (0.69) | ALDH1A1HPGDKDM4EL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333920-A | Benzalphthalides and broad spectrum sun screens | VAN DYK & COMPANY, INC. (US) | 1982-06-08 | — | — | US | claimed |
| CN-108752300-B | Benzylidene phenylene peptide compound, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2022-03-25 | — | — | CN | disclosed |
| CN-108752300-A | Benzyl alkene pitches benzene peptides and its pharmaceutical composition and its application | 中国科学院昆明植物研究所 | 2018-11-06 | — | — | CN | disclosed |
| EP-1216994-B1 | Tricyclic antidepressant derivatives and immunoassay | ROCHE DIAGNOSTICS GMBH (DE) | 2008-12-31 | — | — | EP | disclosed |
| EP-1216994-A2 | Tricyclic antidepressant derivatives and immunoassay | Roche Diagnostics GmbH (DE) | 2002-06-26 | — | — | EP | disclosed |
| US-6368814-B1 | TRICYCLIC ANTIDEPRESSANTS AND METABOLITES THEREOF | ROCHE DIAGNOSTICS CORPORATION | 2002-04-09 | — | — | US | disclosed |
| US-4399141-A | 5-Alkyl or hydroxyalkyl substituted-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines and anticonvulsant use thereof | MERCK & CO., INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4333920-A | Benzalphthalides and broad spectrum sun screens | VAN DYK & COMPANY, INC. (US) | 1982-06-08 | — | — | US | disclosed |