Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | AKT2 | P31751 | 1/20 | 0.47 |
| ▸ | NEK2 | P51955 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5383897 | 0.99 | CYP3A4 (0.47) | CYP3A4KDM4ERECQLAKT2NEK2 | |
| SCHEMBL3435131 | 0.86 | CYP3A4 (0.46) | CYP3A4KDM4ERECQLAKT2NEK2 | |
| SCHEMBL3568644 | 0.86 | KDM4E (0.46) | CYP3A4KDM4ERECQLAKT2NEK2 | |
| SCHEMBL3435695 | 0.86 | CYP3A4 (0.52) | CYP3A4KDM4ERECQLAKT2NEK2 | |
| SCHEMBL4676761 | 0.81 | OPRK1 (0.42) | KDM4ENEK2ALDH1A1LMNAOPRK1 | |
| SCHEMBL3549279 | 0.80 | KDM4E (0.49) | KDM4ENEK2ALDH1A1TDP1ABL1 | |
| SCHEMBL3435672 | 0.80 | NEK2 (0.46) | CYP3A4KDM4ERECQLAKT2NEK2 | |
| SCHEMBL3436043 | 0.79 | AKT2 (0.53) | CYP3A4KDM4ERECQLAKT2NEK2 | |
| SCHEMBL15127625 | 0.78 | KMT2A (0.45) | KDM4EALDH1A1TDP1LMNAOPRK1 | |
| SCHEMBL2080112 | 0.77 | KDM4E (0.67) | KDM4ERECQLAKT2NEK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457199-B1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | OREAL (FR) | 2008-05-14 | — | — | EP | disclosed |
| US-7175670-B2 | Couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-02-13 | — | — | US | disclosed |
| US-7175670-B2 | Couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-02-13 | — | — | US | disclosed |
| EP-1457199-A1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | L'OREAL (FR) | 2004-09-15 | — | — | EP | disclosed |