Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 5/20 | 0.37 |
| ▸ | DHODH | Q02127 | 12/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682523 | 0.90 | PPOX (0.41) | PPOXDHODHMEN1NR1I2KMT2A | |
| SCHEMBL4679803 | 0.88 | PPOX (0.44) | PPOXDHODHMEN1NR1I2KMT2A | |
| SCHEMBL31442437 | 0.88 | PPOX (0.44) | PPOXDHODHMEN1NR1I2KMT2A | |
| SCHEMBL31442383 | 0.87 | PPOX (0.35) | PPOXDHODHMEN1NR1I2KMT2A | |
| SCHEMBL7531289 | 0.87 | PPOX (0.41) | PPOXDHODHMEN1NR1I2KMT2A | |
| SCHEMBL985555 | 0.86 | PPARG (0.38) | PPOXDHODH | |
| SCHEMBL4681638 | 0.85 | PPOX (0.44) | PPOXDHODH | |
| SCHEMBL4679075 | 0.84 | DHODH (0.38) | PPOXDHODH | |
| SCHEMBL4681148 | 0.84 | PPOX (0.54) | PPOXDHODHMEN1KMT2A | |
| SCHEMBL8063467 | 0.83 | PPOX (0.37) | PPOXDHODHMEN1NR1I2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850227-B1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2008-01-09 | — | — | EP | claimed |