Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.72 |
| ▸ | PPARD | Q03181 | 14/20 | 0.72 |
| ▸ | PPARG | P37231 | 9/20 | 0.72 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679328 | 0.92 | PPARA (0.73) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL4677786 | 0.91 | PPARA (0.59) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL4679920 | 0.90 | PPARA (0.71) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL4681176 | 0.89 | PPARA (0.69) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL4678926 | 0.88 | PPARA (0.76) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL4678911 | 0.88 | PPARD (0.68) | PPARAPPARDPPARG | |
| SCHEMBL14446027 | 0.87 | PPARD (0.59) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL4678992 | 0.85 | PPARA (0.71) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL4681892 | 0.83 | PPARD (0.61) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL14445995 | 0.82 | PPARA (0.59) | PPARAPPARDPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513796-B1 | PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORP (US) | 2008-02-13 | — | — | EP | claimed |
| US-20050222424-A1 | Phenyloxyalkanonic acid derivatives as hppar activators | SMITHKLINE BEECHAM CORPORATION | 2005-10-06 | — | — | US | claimed |
| EP-1513796-B1 | PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORP (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-20050222424-A1 | Phenyloxyalkanonic acid derivatives as hppar activators | SMITHKLINE BEECHAM CORPORATION | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222424-A1 | Phenyloxyalkanonic acid derivatives as hppar activators | CEL, HPN, LIPA | PPARA 54/4885PPARD 223/4885PPARG 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.