Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3033331 | 0.88 | ALDH1A1 (0.55) | PDE4BRAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL4058811 | 0.85 | PDE4B (0.70) | PDE4BRAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL4707865 | 0.84 | PDE4B (0.62) | PDE4BRAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL4706084 | 0.82 | PDE4B (0.62) | PDE4BRAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL3033443 | 0.82 | PDE4B (0.59) | PDE4BRAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL4708479 | 0.81 | PDE4B (0.58) | PDE4BRAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL4706986 | 0.80 | PDE4B (0.57) | PDE4BRAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL1652702 | 0.80 | PDE4B (0.52) | PDE4BRAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL3022253 | 0.80 | PDE4B (0.50) | PDE4BRAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL4707672 | 0.80 | PDE4B (0.47) | PDE4BRAB9ASMN1; SMN2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575926-B1 | NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES | ALMIRALL LAB (ES) | 2008-03-05 | — | — | EP | claimed |