Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | SNCA | P37840 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 6/20 | 0.32 |
| ▸ | RXRB | P28702 | 3/20 | 0.32 |
| ▸ | RXRG | P48443 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 7/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4495310 | 0.76 | CYP1A2 (0.44) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL1659293 | 0.70 | CYP1A2 (0.44) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL19167425 | 0.70 | CYP1A2 (0.40) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL19227398 | 0.70 | ALDH1A1 (0.41) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL20182428 | 0.70 | CYP1A2 (0.53) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL4105308 | 0.70 | CYP1A2 (0.53) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL1634590 | 0.70 | ALDH1A1 (0.41) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL9580605 | 0.70 | RARB (0.38) | CYP1A2ALDH1A1PTGS1LMNADRD3 | |
| SCHEMBL258350 | 0.67 | — | — | |
| SCHEMBL19928616 | 0.67 | ALDH1A1 (0.42) | CYP1A2ALDH1A1PTGS1LMNADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083682-B | A kind of preparation method of the carotenal of β Apos 8 ' | 广州巨元生化有限公司 | 2017-10-27 | — | — | CN | claimed |
| CN-105884823-A | Method for preparing 2,6,6-trimethyl-1-cyclohexenyl methylphosphonate | 肇庆巨元生化有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-105646311-A | Method for preparing beta-Apo-8'-carotenal | 广州巨元生化有限公司 | 2016-06-08 | — | — | CN | claimed |
| US-20080076762-A1 | Novel 4-Aminopiperidine Derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2008-03-27 | — | — | US | claimed |
| EP-1824822-A2 | NOVEL 4-AMINOPIPERIDINE DERIVATIVES AS PLASMEPSIN II INHIBITORS | Actelion Pharmaceuticals Ltd. (CH) | 2007-08-29 | — | — | EP | claimed |
| WO-2006056930-A2 | NOVEL 4 -AMINOPIPERIDINE DERIVATIVES AS PLASMEPSIN II INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-06-01 | — | — | WO | claimed |
| US-4073813-A | PLATINUM REDUCTION CATALYST, ALDEHYDES, HYDROGEN | RHONE-POULENC INDUSTRIES (FR) | 1978-02-14 | — | — | US | claimed |
| CN-106083682-B | A kind of preparation method of the carotenal of β Apos 8 ' | 广州巨元生化有限公司 | 2017-10-27 | — | — | CN | disclosed |
| CN-106083682-A | A kind of preparation method of β apo-8 ' carotenal | 广州巨元生化有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105646311-A | Method for preparing beta-Apo-8'-carotenal | 广州巨元生化有限公司 | 2016-06-08 | — | — | CN | disclosed |
| EP-1392655-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2008-07-16 | — | — | EP | disclosed |
| US-20080076762-A1 | Novel 4-Aminopiperidine Derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2008-03-27 | — | — | US | disclosed |
| EP-1198456-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2007-09-19 | — | — | EP | disclosed |
| EP-1198456-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2002-04-24 | — | — | EP | disclosed |
| US-20020028836-A1 | Potassium channel openers | ABBVIE INC. | 2002-03-07 | — | — | US | disclosed |
| WO-2001016138-A1 | SULFONYLPHENYLPYRAZOLE COMPOUNDS USEFUL AS COX-2 INHIBITORS | ABBOTT LABORATORIES (US) | 2001-03-08 | — | — | WO | disclosed |
| WO-2001009096-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2001-02-08 | — | — | WO | disclosed |
| EP-0046606-A1 | Oxygenated alicyclic compounds, process for their preparation and their use as starting materials in the preparation of cyclohexadienic compounds | FIRMENICH SA (CH) | 1982-03-03 | — | — | EP | disclosed |
| US-4105697-A | Process for the preparation of α, β-ethylenic aldehydes | RHONE-POULENC INDUSTRIES (FR) | 1978-08-08 | — | — | US | disclosed |
| US-4073813-A | PLATINUM REDUCTION CATALYST, ALDEHYDES, HYDROGEN | RHONE-POULENC INDUSTRIES (FR) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028836-A1 | Potassium channel openers | KCNJ2, KCNJ11, KCNJ1 | CYP1A2 1723/4885ALDH1A1 704/4885PTGS1 286/4885 |
| US-20080076762-A1 | Novel 4-Aminopiperidine Derivatives | METAP1, DNPEP, PEPD | CYP1A2 538/4885ALDH1A1 1303/4885PTGS1 1036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.