⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21496363 | 0.77 | ALDH1A1 (0.43) | — | |
| SCHEMBL6993215 | 0.74 | — | — | |
| SCHEMBL945096 | 0.74 | — | — | |
| SCHEMBL10959531 | 0.74 | — | — | |
| SCHEMBL6969872 | 0.72 | — | — | |
| SCHEMBL10665821 | 0.72 | — | — | |
| SCHEMBL1040559 | 0.72 | — | — | |
| SCHEMBL1417216 | 0.72 | — | — | |
| SCHEMBL16318511 | 0.72 | — | — | |
| SCHEMBL5061084 | 0.70 | HDAC3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945448-B1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES (JP) | 2008-11-26 | — | — | EP | disclosed |
| US-6020496-A | 5-alkoxy-2(3H)-oxazolone compounds and process for preparing the same | UBE INDUSTRIES, LTD. (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0945448-A1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES, LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-4652269-A | Process for the continuous trichromatic dyeing of synthetic polyamide materials: including a blue anthraquinone reactive dye | CIBA-GEIGY CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |
| US-4389416-A | DIURETICS | ABBOTT LABORATORIES (US) | 1983-06-21 | — | — | US | disclosed |
| US-4228259-A | FROM A POLYAMINO-AMIDE AND A CHROMOPHORE OR CHROMOGEN GROUP | L'OREAL (FR) | 1980-10-14 | — | — | US | disclosed |