Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 7/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.61 |
| ▸ | TTR | P02766 | 3/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 5/20 | 0.53 |
| ▸ | BCR | P11274 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679562 | 1.00 | CYP1A1 (0.61) | CYP1A1CYP1B1ALOX5PTGS2TTR | |
| SCHEMBL28981586 | 0.90 | CYP1A1 (0.64) | CYP1A1CYP1B1ALOX5PTGS2TTR | |
| SCHEMBL28981584 | 0.90 | CYP1A1 (0.64) | CYP1A1CYP1B1ALOX5PTGS2TTR | |
| SCHEMBL14416282 | 0.85 | CYP1A1 (0.61) | CYP1A1CYP1B1ALOX5PTGS2TTR | |
| SCHEMBL17655776 | 0.85 | CYP1A1 (0.61) | CYP1A1CYP1B1ALOX5PTGS2TTR | |
| SCHEMBL17469176 | 0.84 | CYP1A1 (0.50) | CYP1A1CYP1B1ALOX5PTGS2TTR | |
| SCHEMBL14143445 | 0.84 | ALOX5 (0.59) | CYP1A1CYP1B1ALOX5PTGS2TTR | |
| SCHEMBL19295407 | 0.82 | BACE1 (0.57) | CYP1A1CYP1B1ALOX5PTGS2TTR | |
| SCHEMBL9605433 | 0.79 | CYP1A1 (0.67) | CYP1A1CYP1B1ALOX5PTGS2TTR | |
| SCHEMBL12729847 | 0.77 | CYP1A1 (0.65) | CYP1A1CYP1B1ALOX5PTGS2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386913-B1 | PYRROLE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-7220773-B2 | Heterocylic amines used as antidiabetic or hyperglycemic agents | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| US-20040162331-A1 | Pyrrole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2004-08-19 | — | — | US | disclosed |
| EP-1386913-A1 | PYRROLE DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162331-A1 | Pyrrole derivative | SLC5A1, GLP1R, SLC5A2 | CYP1A1 1151/4885CYP1B1 697/4885ALOX5 3114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.