SCHEMBL4679630

SCHEMBL4679630

CC(C)(C)OC(=O)C(C)(C)[NH]

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.50
USP2 O75604 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAPK1 P28482 1/20 0.31
ELANE P08246 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4677923 0.79 DGAT1 (0.52) DGAT1USP2SMN1; SMN2ELANETDP1
SCHEMBL14606262 0.77 DGAT1 (0.50) DGAT1USP2SMN1; SMN2MAPK1ELANE
SCHEMBL307610 0.75 DGAT1 (0.55) DGAT1USP2SMN1; SMN2ELANETDP1
SCHEMBL3141601 0.75 DGAT1 (0.79) DGAT1USP2SMN1; SMN2ELANETDP1
Hydrogen Peroxide SCHEMBL25411902 0.73 DGAT1 (0.52) DGAT1USP2SMN1; SMN2ELANEALDH1A1
SCHEMBL20565054 0.73 DGAT1 (0.52) DGAT1USP2SMN1; SMN2ELANETDP1
SCHEMBL8207418 0.73 DGAT1 (0.52) DGAT1USP2SMN1; SMN2ELANETDP1
SCHEMBL362903 0.73 DGAT1 (0.52) DGAT1USP2SMN1; SMN2ELANETDP1
SCHEMBL4672716 0.73
SCHEMBL4674911 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095935-B1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL CO (JP) 2008-12-17 EP disclosed
US-6410484-B1 ACTIVE MATERIAL; CONTROLLING WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US disclosed
EP-1095935-A1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-02 EP disclosed