Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.41 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27623125 | 1.00 | CHEK1 (0.41) | CHEK1FYNPDGFRBPIM1FGFR1 | |
| SCHEMBL4845273 | 0.87 | FYN (0.47) | CHEK1FYNPDGFRBPIM1FGFR1 | |
| SCHEMBL4845283 | 0.87 | FYN (0.47) | CHEK1FYNPDGFRBPIM1FGFR1 | |
| SCHEMBL14181799 | 0.70 | ITGB3 (0.43) | ALDH1A1GAAGFERITGA4ITGB7 | |
| SCHEMBL8326273 | 0.68 | ITGB3 (0.41) | ALDH1A1GAAGFERITGA4ITGB7 | |
| SCHEMBL7233451 | 0.65 | PTPRB (0.45) | ALDH1A1MAPTPKMRECQL | |
| SCHEMBL23033538 | 0.65 | CA12 (0.48) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL14907948 | 0.64 | GAA (0.52) | ALDH1A1GAAGFERHDAC1 | |
| SCHEMBL28322179 | 0.64 | CYP1A2 (0.44) | KMT2AMEN1AAK1CFTR | |
| SCHEMBL13099832 | 0.64 | KCNN4 (0.44) | GAAKMT2AMEN1MAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594853-B1 | METHOD FOR THE PRODUCTION OF BICYCLIC AROMATIC AMINO ACIDS AND INTERMEDIATE PRODUCTS THEREOF | MERCK PATENT GMBH (DE) | 2008-07-09 | — | — | EP | disclosed |
| EP-1594853-A1 | METHOD FOR THE PRODUCTION OF BICYCLIC AROMATIC AMINO ACIDS AND INTERMEDIATE PRODUCTS THEREOF | MERCK PATENT GmbH (DE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004072054-A1 | METHOD FOR THE PRODUCTION OF BICYCLIC AROMATIC AMINO ACIDS AND INTERMEDIATE PRODUCTS THEREOF | MERCK PATENT GMBH (DE) | 2004-08-26 | — | — | WO | disclosed |