SCHEMBL4680771

SCHEMBL4680771

CC(=O)N[C@H]1[C@H]([C@H](OC(=O)Oc2ccc([N+](=O)[O-])cc2)[C@H]2COC(=O)O2)OC(C(=O)O)=C[C@@H]1N/C(=N\C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4680785 1.00
SCHEMBL14524123 0.95 ALDH1A1 (0.30)
SCHEMBL14590945 0.95 ALDH1A1 (0.30)
SCHEMBL14498377 0.95 ALDH1A1 (0.30)
SCHEMBL14340347 0.95 ALDH1A1 (0.30)
SCHEMBL14523566 0.93
SCHEMBL14498369 0.93
SCHEMBL26839832 0.88 ALDH1A1 (0.31)
SCHEMBL26951193 0.87
SCHEMBL15218216 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1423385-B1 INTERMEDIATES FOR PREPARING NEURAMINIDASE INHIBITOR CONJUGATES BIOTA SCIENT MANAGEMENT (AU) 2008-07-02 EP disclosed
US-7230114-B2 Intermediates for preparing neuraminidase inhibitor conjugates BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2007-06-12 US disclosed
US-20050032853-A1 Intermediates for preparing neuraminidase inhibitor conjugates BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2005-02-10 US disclosed
EP-1423385-A4 INTERMEDIATES FOR PREPARING NEURAMINIDASE INHIBITOR CONJUGATES BIOTA SCIENT MANAGEMENT (AU) 2004-12-01 EP disclosed
EP-1423385-A1 INTERMEDIATES FOR PREPARING NEURAMINIDASE INHIBITOR CONJUGATES BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) 2004-06-02 EP disclosed
WO-2003022841-A1 INTERMEDIATES FOR PREPARING NEURAMINIDASE INHIBITOR CONJUGATES BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2003-03-20 WO disclosed