Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.38 |
| ▸ | FEN1 | P39748 | 5/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 12/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680779 | 0.71 | LMNA (0.39) | ALOX5APFEN1FPR2F10F9 | |
| SCHEMBL4680778 | 0.70 | F10 (0.41) | ALOX5APFEN1FPR2F10F9 | |
| SCHEMBL4686406 | 0.67 | F10 (0.50) | FPR2F10 | |
| SCHEMBL4680650 | 0.66 | F10 (0.51) | FPR2F10 | |
| SCHEMBL4680114 | 0.66 | F10 (0.42) | ALOX5APFEN1FPR2F10 | |
| SCHEMBL4680194 | 0.66 | F10 (0.42) | ALOX5APFEN1FPR2F10F9 | |
| SCHEMBL4680797 | 0.66 | F10 (0.49) | F10 | |
| SCHEMBL4680260 | 0.66 | F10 (0.53) | FPR2F10 | |
| SCHEMBL4680196 | 0.65 | F10 (0.41) | ALOX5APFEN1FPR2F10 | |
| SCHEMBL4680888 | 0.65 | F10 (0.39) | ALOX5APFEN1FPR2F10F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337251-B1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2008-08-20 | — | — | EP | claimed |
| EP-1337251-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-08-27 | — | — | EP | claimed |
| WO-2002102380-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-12-27 | — | — | WO | claimed |