Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.38 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.38 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47058 | 0.93 | F10 (0.42) | F10TRPA1MAPTLMNAMEN1 | |
| SCHEMBL10226260 | 0.93 | F10 (0.41) | F10TRPA1MAPTLMNAMEN1 | |
| SCHEMBL46581 | 0.89 | F10 (0.43) | F10TRPA1MAPTLMNAMEN1 | |
| SCHEMBL46822 | 0.88 | MAPT (0.40) | F10TRPA1MAPTLMNAMEN1 | |
| SCHEMBL44799 | 0.87 | PHGDH (0.46) | F10TRPA1MAPTLMNAMEN1 | |
| SCHEMBL46889 | 0.87 | F10 (0.37) | F10TRPA1MAPTLMNAMEN1 | |
| SCHEMBL10225110 | 0.87 | SERPINE1 (0.39) | F10TRPA1MAPTLMNAMEN1 | |
| SCHEMBL46832 | 0.86 | F10 (0.44) | F10TRPA1MAPTLMNAMEN1 | |
| SCHEMBL45411 | 0.86 | PPARG (0.38) | F10TRPA1MAPTLMNAMEN1 | |
| SCHEMBL10225259 | 0.86 | TRPA1 (0.37) | F10TRPA1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |