Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4676429 | 0.87 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL4678418 | 0.84 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL4681729 | 0.83 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL4681583 | 0.83 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL4677627 | 0.80 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL4676765 | 0.80 | CNR1 (0.50) | CNR1CNR2 | |
| SCHEMBL4683481 | 0.80 | CNR1 (0.50) | CNR1CNR2 | |
| SCHEMBL4677739 | 0.75 | LIPE (0.52) | CNR1CNR2LIPE | |
| SCHEMBL4682588 | 0.74 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL4684187 | 0.74 | CNR1 (0.42) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638953-B1 | 3-SUBSTITUTED 5,6-DIARYL-PYRAZINE-2-CARBOXAMIDE AND -2-SULFONAMIDE DERIVATIVES AS CB1 MODULATORS | ASTRAZENECA AB (SE) | 2008-08-27 | — | — | EP | claimed |