Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL4681095

N=C(N)c1ccc(CC(=O)C(=O)O)c(OC[C@@H](CCC(=O)O)NC(=O)c2cccc(-c3cccnc3)c2)c1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F10 P00742 14/20 0.46
F2 P00734 6/20 0.43
PRSS1 P07477 3/20 0.40
HPGDS O60760 1/20 0.37
F7 P08709 3/20 0.36
F3 P13726 3/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
SUCNR1 Q9BXA5 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL4684504 0.93 F10 (0.50) F10F2PRSS1HPGDSF7
Trifluoroacetic Acid SCHEMBL4682216 0.92 F10 (0.48) F10F2PRSS1HPGDSF7
Trifluoroacetic Acid SCHEMBL4685963 0.91 F10 (0.49) F10F2PRSS1HPGDSF7
Trifluoroacetic Acid SCHEMBL4681296 0.89 F10 (0.48) F10F2PRSS1HPGDSF7
Trifluoroacetic Acid SCHEMBL4681075 0.88 F10 (0.45) F10F2PRSS1HPGDSPRSS2
Trifluoroacetic Acid SCHEMBL4681672 0.86 F10 (0.48) F10F2F7F3
Trifluoroacetic Acid SCHEMBL4685323 0.84 F10 (0.48) F10F2ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL4687769 0.84 F10 (0.47) F10F2F7F3
Trifluoroacetic Acid SCHEMBL4687059 0.83 AGTR2 (0.48) F10F2F7F3
Trifluoroacetic Acid SCHEMBL4685749 0.83 F10 (0.49) F10F2PRSS1F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1236712-B1 AMIDINOPHENYLPYRUVIC ACID DERIVATIVE AJINOMOTO KK (JP) 2008-08-06 EP disclosed
US-6710056-B2 PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVE AN EXCELLENT ANTAGONISTIC EFFECT AGAINST ACTIVATED BLOOD COAGULATION FACTOR VII. AJINOMOTO CO., INC. (JP) 2004-03-23 US disclosed
US-20030109547-A1 Amidinophenylpyruvic acid derivatives AJINOMOTO CO. INC (JP) 2003-06-12 US disclosed
EP-1236712-A1 AMIDINOPHENYLPYRUVIC ACID DERIVATIVE Ajinomoto Co., Inc. (JP) 2002-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109547-A1 Amidinophenylpyruvic acid derivatives HABP2, F2, F7 F10 26/4885F2 2/4885PRSS1 81/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.