Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 14/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | GLP1R | P43220 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682196 | 0.82 | AVPR2 (0.68) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL4681024 | 0.82 | AVPR2 (0.47) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL8651879 | 0.80 | CYP19A1 (0.36) | AVPR2CYP19A1TBXAS1 | |
| SCHEMBL588265 | 0.77 | AVPR2 (0.48) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL10281095 | 0.74 | AVPR2 (0.69) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL4682042 | 0.71 | AVPR2 (0.59) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL4687535 | 0.70 | AVPR2 (0.60) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL7356522 | 0.69 | AVPR2 (0.66) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL20369018 | 0.69 | AVPR2 (0.66) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL4685226 | 0.69 | AVPR2 (0.67) | AVPR2AVPR1AABCB11ADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |