Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 15/20 | 0.68 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.68 |
| ▸ | HTR1A | P08908 | 2/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | HRH1 | P35367 | 1/20 | 0.68 |
| ▸ | GLP1R | P43220 | 1/20 | 0.68 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.68 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.68 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.68 |
| ▸ | OXTR | P30559 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684961 | 0.85 | AVPR2 (0.79) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL4696624 | 0.85 | AVPR2 (0.69) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| Hydrochloric Acid SCHEMBL4685822 | 0.84 | AVPR2 (0.68) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL4682042 | 0.84 | AVPR2 (0.59) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL1462502 | 0.83 | AVPR2 (0.71) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL4687535 | 0.83 | AVPR2 (0.60) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| Hydrochloric Acid SCHEMBL4685226 | 0.82 | AVPR2 (0.67) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL4682193 | 0.82 | AVPR2 (0.44) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL4681027 | 0.82 | AVPR2 (0.71) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| Hydrochloric Acid SCHEMBL4684940 | 0.82 | AVPR2 (0.68) | AVPR2AVPR1AABCB11HTR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |