SCHEMBL4682833

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4683032	0.93	CYP19A1 (0.40)	GRM5KDM4EHPGDMAPTUSP2
	SCHEMBL4683106	0.92	MAPT (0.39)	GRM5KDM4EHPGDMAPTUSP2
	SCHEMBL4680210	0.89	GRM5 (0.42)	GRM5KDM4EHPGDMAPTUSP2
	SCHEMBL4680527	0.83	GRM5 (0.42)	GRM5KDM4ENPC1RAB9AALDH1A1
	SCHEMBL4740959	0.82	GRM5 (0.46)	GRM5KDM4EHPGDNPC1RAB9A
	SCHEMBL4683592	0.82	ALDH1A1 (0.43)	GRM5KDM4EHPGDMAPTNPC1
	SCHEMBL4679544	0.81	GRM5 (0.45)	GRM5KDM4EHPGDMAPTUSP2
	SCHEMBL4421918	0.80	GRM5 (0.46)	GRM5KDM4EHPGDMAPTUSP2
	SCHEMBL4421378	0.80	GRM5 (0.46)	GRM5KDM4EHPGDMAPTUSP2
	SCHEMBL5039087	0.79	GRM5 (0.57)	GRM5KDM4EHPGDMAPTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.