Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687649 | 0.98 | HTT (0.43) | PKMHTTGFERKMT2AMAPK14 | |
| SCHEMBL7350714 | 0.93 | HTT (0.44) | PKMHTTGFERKMT2AMAPK14 | |
| SCHEMBL7354366 | 0.87 | KMT2A (0.47) | PKMHTTGFERKMT2AMAPK14 | |
| SCHEMBL4682892 | 0.83 | HTT (0.42) | PKMHTTGFERKMT2AHSP90AA1 | |
| SCHEMBL4687648 | 0.81 | KMT2A (0.43) | PKMHTTGFERKMT2AHSP90AA1 | |
| SCHEMBL8906020 | 0.79 | HTT (0.41) | PKMHTTGFERKMT2AHSP90AA1 | |
| SCHEMBL7350710 | 0.79 | HTT (0.44) | PKMHTTGFERKMT2AHSP90AA1 | |
| SCHEMBL4685852 | 0.77 | ALDH1A1 (0.56) | PKMKMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL4684788 | 0.77 | ALDH1A1 (0.56) | PKMKMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL4687627 | 0.75 | ALDH1A1 (0.57) | PKMKMT2AALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |