Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.80 |
| ▸ | PPARA | Q07869 | 7/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683389 | 1.00 | PPARG (0.80) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL4679556 | 0.90 | PPARG (0.66) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL14143473 | 0.90 | PPARG (0.68) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL4679548 | 0.90 | PPARG (0.66) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL2719814 | 0.89 | PPARG (0.67) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL2719820 | 0.89 | PPARG (0.67) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL14143467 | 0.89 | PPARG (0.70) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL2717139 | 0.88 | PPARG (0.66) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL2717135 | 0.88 | PPARG (0.66) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL4680580 | 0.88 | PPARG (0.63) | PPARGPPARAALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386913-B1 | PYRROLE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| EP-1386913-B1 | PYRROLE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-7220773-B2 | Heterocylic amines used as antidiabetic or hyperglycemic agents | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| US-7220773-B2 | Heterocylic amines used as antidiabetic or hyperglycemic agents | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |